Carrier Set
Na voljo (Čas dostave: 2-5 delovnih dni)
Več kot 30 let izkušenj
in celovita storitev iz enega vira – od namestitve do vzdrževanja, s hitro dostavo in zanesljivo podporo.
Dodatne informacije
Detection, by allelic discrimination, of the DPYD gene polymorphisms ,associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).
Main features
Detection, by allelic discrimination, of the DPYD gene polymorphisms DPYD*2A (IVS14+1G>A,c.1905+1G>A,rs3918290), DPYD*13 (c.1679T>G,rs55886062), DPYD D949V (c.2846A>T, rs67376798) and DPYD IVS10 (c.1129–5923C>G, rs75017182),associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).
Controls
The kit is provided with the following controls:
- DPYD WT positive control: Positive control DNA containing a mixture of synthetic wild-type DNA sequences for the DPYD polymorphisms analyzed;
- DPYD MT positive control: Positive control DNA containing a mixture of synthetic mutant DNA sequences for the DPYD polymorphisms analyzed;
- Negative control.
Starting material
The kit allows the analysis of genomic DNA extracted from whole blood.