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  • EasyPGX ready DPYD Kit, 48 tests

EasyPGX ready DPYD Kit, 48 tests

  • Item No. 11037658
  • Ref.No. RT026
  • Diatech Pharmacogenetics
Suitable for:
  • EasyPGX qPCR instrument 96
Delivery / installation will take place shortly after order confirmation

30+ years of experience

and end-to-end service from a single source – from installation to maintenance, with fast delivery and reliable support.

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Further Information

Detection, by allelic discrimination, of the DPYD gene polymorphisms ,associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).

Main features

Detection, by allelic discrimination, of the DPYD gene polymorphisms DPYD*2A (IVS14+1G>A,c.1905+1G>A,rs3918290), DPYD*13 (c.1679T>G,rs55886062), DPYD D949V (c.2846A>T, rs67376798) and DPYD IVS10 (c.1129–5923C>G, rs75017182),associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).

Controls

The kit is provided with the following controls:

  • DPYD WT positive control: Positive control DNA containing a mixture of synthetic wild-type DNA sequences for the DPYD polymorphisms analyzed;
  • DPYD MT positive control: Positive control DNA containing a mixture of synthetic mutant DNA sequences for the DPYD polymorphisms analyzed;
  • Negative control.

Starting material

The kit allows the analysis of genomic DNA extracted from whole blood.


Related items

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EasyPGX qPCR instrument 96
CE-IVD validated and complete diagnostic solutions for the detection and analysis of somatic gene variants in oncology. The EasyPGx® line is a fully integrated solution for qPCR amplification, detection and data analysis. It combines the thermal cycler, the necessary ancillary equipment and the software. The ready-to-use and lyophilized EasyPGX® Ready reagents are used with it.
  • Item No. 11003902
  • Ref.No. RT800-96
  • Diatech Pharmacogenetics
Delivery / installation will take place shortly after order confirmation

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