Carrier Set

N° d’art. 12072927
N° de réf. CARRIERSET
Sansure

Disponible (Délai de livraison: 2-5 jours ouvrables)

Plus de 30 ans d'expérience

et un service complet auprès d'un seul interlocuteur – de l'installation à la maintenance, avec une livraison rapide et un support fiable.

Informations complémentaires

Detection, by allelic discrimination, of the DPYD gene polymorphisms ,associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).

Main features

Detection, by allelic discrimination, of the DPYD gene polymorphisms DPYD*2A (IVS14+1G>A,c.1905+1G>A,rs3918290), DPYD*13 (c.1679T>G,rs55886062), DPYD D949V (c.2846A>T, rs67376798) and DPYD IVS10 (c.1129–5923C>G, rs75017182),associated with the toxicity due to the treatment with Fluoropyrimidines, using 4 oligo mixes. Each mix allows the co-amplification of the mutant sequence (FAM) as well as the wild-type sequence (HEX).

Controls

The kit is provided with the following controls:

DPYD WT positive control: Positive control DNA containing a mixture of synthetic wild-type DNA sequences for the DPYD polymorphisms analyzed;
DPYD MT positive control: Positive control DNA containing a mixture of synthetic mutant DNA sequences for the DPYD polymorphisms analyzed;
Negative control.

Starting material

The kit allows the analysis of genomic DNA extracted from whole blood.

Carrier Set

Informations complémentaires

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