PCR-Box ResistanceDetection of resistance marker genes (step 2/3)

Cube Dx molecular pathogen testing assists microbiologists and infectiologists in the early detection of a pathogen in whole blood and other sample types. This is especially important for microorganisms that have been weakened by antimicrobial treatment or that show slow growth in or on microbiological culture media.

The procedure is composed of 3 steps:

1. Sample preparation with GINA (whole blood) or LINA (positive blood culture, BAL).
2. Detection (PCR-Box Bacteria, PCR-Box Resistance, PCR-Box Fungi)
3. Identification (hybcell Pathogens, hybcell Bacteria, hybcell Fungi)

Step 2 and step 3 can be summarized as compact sequencing. A positive PCR result is followed by the identification and, if applicable, detection of resistance genes of the pathogen in the hybcell.

The advantages for your laboratory:

• Sensitive and parallel identification of bacteria, fungi and resistance genes within 3 hours from whole blood - same day.
• Identification of multiple pathogens/mixed infections possible
• Low sample volume (500µl) - sepsis diagnostics for all wards (including pediatrics, neonatology)
• Modular system - decide which panel you want to use
• Step-by-step diagnostics - adapt the costs to the result